Category: News

Diets rich in Omega-3s provide boosts to health, especially during and after cancer treatment

Typically, medical interventions like chemotherapy and radiation are used as a bulwark against cancer, but what you eat in a day can play more of a role than you would think in fighting this common disease. Specifically with prostate and breast cancer, certain additions to a healthy diet can provide boosts to either prevention, continued efforts against the growth of cancer, or post-cancer health. 

Some recent research studies, available on the Seafood Industry Research Fund (SIRF) website, looked in depth on how incorporating Omega-3 fatty acids into a diet can be useful against cancer. Omega-3s are essential fats that support heart and brain health and are found in fatty fish such as salmon, trout, sardines and tuna. Due to providing these anti-inflammatory properties, its use against cancer is scientifically intriguing. 

One article, titled “Feasibility of Investigational Procedures and Efficacy of a Personalized Omega-3 Dietary Intervention in Alleviating Pain and Psychoneurological Symptoms in Breast Cancer Survivors,” discusses how breast cancer patients sometimes struggle with psychoneurological symptoms (PNS) after treatment and deal with high inflammation. Omega-3s are anti-inflammatory. By correlating the two together, researchers from University of Connecticut conducted a study which showed that a diet of high Omega-3s in breast cancer survivors can have a “significant decrease in pain, perceived stress, sleep, depression, and fatigue over the course of intervention.” 

Similarly, in another study by the University of Connecticut, titled “Dietary Consumption Patterns in Breast Cancer Survivors: Pilot Evaluation of Diet, Supplements, and Clinical Factors,” the aim was to evaluate dietary quality in a cohort of breast cancer survivors. In this study, results found that many women are not meeting recommended dietary guidelines. Yet the results also indicated that by incorporating a high amount of Omega-3s, including in supplements, it promoted better nutritional consumption patterns and improved overall health during survivorship after cancer.  

Both studies point to the impact Omega-3s can have on the body. Increased consumption of Omega-3s can be an aid against the sometimes obstructive aftereffects of battling breast cancer. Eating more seafood is a good step to take on the road to full recovery.  

Men can also experience positive effects from a diet of Omega-3s. Dr. William Aronson, at UCLA, spends time researching how Omega-3s can delay the progression of prostate cancer. His continued efforts are reflected in two research papers: “Effect of Omega-3 Fatty Acid Diet on Prostate Cancer Progression and Cholesterol Efflux in Tumor Associated Macrophages” and “High Omega-3, Low Omega-6 Diet with Fish Oil for Men with Prostate Cancer on Active Surveillance.”  Preclinical and clinical translational research supports the role of an Omega-3 fatty acid diet for prostate cancer prevention and treatment, according to the study.  

In this study, men on active surveillance for prostate cancer were randomly assigned to one of two groups: a control group or a group on the high Omega-3 diet. After one year, they were evaluated to observe the change of the Ki-67 index which is a protein marker for cancer growth. A high amount of Ki-67 in the body suggests a higher rate of progression of prostate cancer. An increased intake of fish and other foods high in Omega-3s, with a lowered intake of Omega-6s, such as corn oil, safflower oil, and fried foods, showed a decrease in the biomarker Ki-67, which is positive. 

Overall, whether someone has breast cancer, prostate cancer, or just looking to eat healthier, eating more foods high in Omega-3s should be encouraged. Dr. Aronson is continuing to study these effects and other researchers are too, as delaying cancer progression and reducing inflammation in the human body are top goals many have in the fight against cancer. People with prostate or breast cancer can benefit from these findings and with a simple change to certain aspects of their diet may find many encouraging outcomes.

By Maia LeClair, SIRF intern  

Dr. William Aronson discusses his study on how Omega-3s can be used in diet to slow progression of prostate cancer

Catching cancer early and treating it fast is one of the leading drivers of investment, research, and study in the field of cancer research. With so many affected by cancer every year, clinical trials indicating actionable steps for patients, while not necessarily a cure, can still be a lifeline. The concern for many with cancer is the threat of metastasizing, or fast-growing tumors unwilling to be halted. But are there other considerations in what could play a role in the progression of cancer? Dr. William Aronson, a Professor at UCLA in the Department of Urology, has dedicated years to the study of how Omega-3s, a type of fatty acid easily found in fish, can be used within a diet to slow the progression of prostate cancer. His recent study, titled High Omega-3, low Omega-6 diet with fish oil for men with prostate cancer on active surveillance: the CAPFISH-3 randomized clinical trial, can be found on the Seafood Industry Research Fund (SIRF) website.  

Dr. Aronson’s work typically focuses on the quantity of dietary fat, omega-3 fatty acids from fish oil, caloric restriction, green tea, and lycopene in a diet. He conducts clinical research on the role of these nutritional elements in the treatment of prostate cancer. His research has focused on the general efficacy of incorporating these elements into one’s diet. And what he’s found seems to be positive.  

“The background is that in our animal models and in prior short-term clinical studies, we’ve clearly seen the potential for dietary fat changes combined with fish with Omega-3 fats for delaying prostate cancer progression,” Aronson said.  

His studies, which date back more than 25 years, are driven by this look into how diet affects one’s health, while having a type of mindset of “you are what you eat.”  

“There have been epidemiologic studies suggesting that increased fish intake delays the progression of prostate cancer,” Aronson said. “The studies for prevention are actually less clear, but there are very nice prior studies that involve fish intake for delaying progression.” 

In this case, the studies conducted showed results of how increased fish intake, while lowering fat intake of ingredients, such as corn oil, safflower oil, and fried foods, significantly lowered the biomarker protein Ki-67, which can predict prostate cancer progression. Ki-67 is a protein on the surface of cancer cells which is a marker for cells actively dividing and the cancer growing. Prostate cancers with higher Ki-67 levels are more likely to spread outside the prostate leading to cancer progression and limiting life expectancy 

 Dr. Aronson’s study observed the rates of Ki-67 significantly declined because of the changed diet.  

“We found that through this dietary intervention, which involved increased fish intake, we were able to lower the Ki-67 level in prostate cancer cells in these patients, as compared to a control group,” Aronson said. 

Dr. Aronson said in prior studies, he and his team found that the omega-3 fats actually inhibit a cell in the immune system that prostate cancer uses to promote its own growth. They are interested in applying this favorable effect of fish-derived omega-3 fats in future clinical trials with the hope of slowing the progression of more advanced prostate cancer. 

Ultimately, these studies and clinical trials are encouraging dietary changes in the hope of slowing the progression of this cancer, which is the second leading cause of cancer in men. Due to its high prevalence, Aronson said the key is to share these findings with clinicians and patients who might benefit from them. 

For Dr. Aronson, these clinical trials are the culmination of years of hard work. Working with funding from the National Cancer Institute and private donors has all led up to the end results of this particular trial.  

“To see our positive findings was so gratifying,” Aronson said. “In that moment when the statisticians let us know our favorable results, that was really among the most exciting moments in my career. We believe our findings will be of tremendous benefit to our patients with prostate cancer.” 

Dr. Aronson and his team are presently analyzing the samples from the patients, both blood and tissue samples, to further understand exactly how the fish-based intervention had such a positive impact.   

“We’ve got some hard work ahead of us,” Aronson said. “Our findings were positive, but there’s more work to be done.” 

Science and technology are ever evolving, and Aronson isn’t stopping here. He believes the future will hold more concrete ways of prevention and treatment for cancer with diet and lifestyle changes. For now, Aronson’s findings help create hope. It is exciting that incorporating more seafood, one of the easiest meals to cook, into one’s diet can have benefits that go past the usual health food conversations and potentially have a direct impact on the progression of prostate cancer.  

By Maia LeClair, SIRF intern

Q&A With the Researchers Exploring the Ability to Extract Plasmalogens from Marine Organisms

This video interview with Alexander Chouljenko, Gabe Dough, Eric Herbst explains a research project that SIRF is funding at North Carolina State University that is exploring the ability to extract plasmalogens from marine organisms like sea squirts, bay scallops and ribbed mussels. Plasmalogens are said to have cognitive benefits that could be able to fight against cognitive diseases like Alzheimer’s. If this exploratory research is a success, then these marine organisms could be farmed with aquaculture for the biotech or the nutraceutical industries.  

John P. Connelly Memorial Fund successfully met its goal

The John P. Connelly Memorial Fund has successfully met its goal with SIRF Board members’ help by raising $91,725 in donations. The Seafood Industry Research Fund (SIRF) Board created this memorial fund in honor of John Connelly who was the third president of NFI and secretary and treasurer of SIRF from 2003 to 2022. John was a passionate seafood advocate and leader who led fundamental change in the seafood industry. He was a beloved husband, father, and friend with a charismatic personality.  

Donate to the John P. Connelly Memorial Fund here.

Meet SIRF Board Member Christine Ngo 

Ways to describe Christine Ngo: President of H&N Group, Board Member of SIRF and industry powerhouse. Her journey with seafood began with her family. She was born in Vietnam and her family came to America in 1979. Her father went on to start H&N Group’s company back in 1981 as a local distribution company in San Francisco.  

Ngo’s focus remained on her education as she grew; after graduating from college, her mother asked her to join the company. Her mother felt that with her education and experience with the English language she could help to fill any gaps in the company. However, Ngo said that her father didn’t really need her help. “Really he was a self-starter that actually built his company successfully and obtained good employees that helped him along the way as well,” Ngo said.  

Ngo officially joined the company in 1997, and the rest was history.  

Ngo is grateful for the opportunities in the seafood world she has been privy to, which led her to her current position on the SIRF Board of Directors. She was asked to join SIRF in 2019 by John Connelly and Bill Dresser, whom she’d known for years. 

Ngo believes the best part of her work with SIRF is getting to be a part of the research projects, getting to see the projects being presented that are highlighting the technical advances being made in the seafood world. “I think [with] those projects, you just start to see a different dynamic of what it can become,” Ngo said.  

Being on the SIRF Board, Ngo has realized that even though there might be a disagreement over a proposal, it is put on the backburner and all focus is put into the expected result. “And so, when the result comes out to achieve the intended purpose, we all agree. It’s not hard, because we all want to do it for the right reasons,” Ngo said.  

Ngo leads with heart and through adversity. She comes from a humble family that immigrated and feels very fortunate for the success they’ve had. She can focus on the good nature she witnessed from her parents’ hearts and employ in the leadership positions she holds.  

Christine leads through adversity because of the challenges she and her family faced. Being a part of the industry, she has gotten to go out to fish farms and has seen how hard the people work. “It humbles you in a way that you need to respect all people in the value chain, not just product, but certainly people overall,” Ngo said. 

When discussing the world of seafood sustainability and research, Ngo believes that food safety is the number one priority. She believes that sustainability used to take priority, but with social media’s quick turnaround, achieving sustainability is an endless goal. The greatest focus now needs to be on food safety and ensuring more research and correct information is being put into the stream of media.  

Outside of seafood, Christine has three boys and a family that is very close. Her hands are full, but her heart is filled with love. Her second love is food and travel. “I will travel for food. I prefer to go to a restaurant more than I would like to go to a monument,” she said.  

She believes there’s no better way to understand a culture than to physically digest it. With her family’s background in seafood, Ngo has been able to travel the world from a young age.  Being able to enjoy seafood cuisine from all over the world, Ngo said she thinks “what we all love about the seafood world is that we also get to eat it.”  

Meet SIRF Board Member Bill Dresser  

Meet Bill Dresser, a man of land and water (mainly water), also known as the CEO/owner of Sea Port Products Corporation and Seafood Industry Research Fund (SIRF) board member. Dresser’s unexpected journey in the seafood industry began about 43 years ago when his father started a seafood company.  

From the beginning, Sea Port Products Corporation was dedicated to ethically sourcing seafood from the best global providers. Dresser explained that at the time, he was going to become a lawyer, but his father asked him if he would put a pause on law school and come help him start the business. “And that was back in 1981 and I’m so glad he did that, because I’ve never looked back, but it was my dad and his vision.” Dresser said. 

Dresser’s journey with SIRF started when he was a chairman at the National Fisheries Institute (NFI), seeing the relationship between NFI and SIRF, which back then was the Fisheries Scholarship Fund (FSF). He recognized SIRF’s potential and later became a full board member.  

Outside of the office (which can happen on rare occasions), Dresser describes himself as a ‘water boy,’ spending most of his time on or in the water, golfing and when able, fishing. Like many in the industry, Dresser has a difficult time nailing down a favorite seafood dish. However, he came to narrow his selection down to raw fish and seasonal items, cherishing the stone crab claw that comes out of Florida or the crab cakes from Maryland.  

When asked about his favorite part of SIRF, he found it difficult to narrow down to just one thing. It’s SIRF’s overall message that means the most to him, the idea of giving back to an industry that has given so much to him. Propelling the industry forward and coming together as a board for a common goal: seafood research and safety.  

Dresser knows the importance of seafood being an ever-changing industry, having to constantly adjust to the challenges they may face. In a time of rapidly changing media and social platforms, information and misinformation regarding seafood spreads quickly.  

“We all believe that seafood is the greatest protein on this planet, we believe that from every standpoint, meaning we think it’s the most sustainable,” Dresser said. He’s incredibly passionate about the ongoing push for sustainability and research being shared within the industry and consumers.   

Dresser believes a common goal is what holds the board to a common understanding, with a variety of different backgrounds providing differing perspectives. He explained that the board has “been diligent to assure that we are getting diverse perspectives and then bringing them to the table” 

Dresser explained that as a board, the most important trait is listening, when the SIRF board discusses what research projects to invest in, it is integral to listen. It’s about finding what is most prescient in the industry, and then being proactive. Finding the line between research and advocacy, as SIRF focuses on research while NFI focuses on advocacy, in a group of diverse backgrounds and different opinions. Dresser has a unique understanding of this balance with his past at NFI and his present at SIRF and Sea Port.  

When thinking about the future of seafood and sustainability, Dresser recounts his journey with the industry: “When I started 43 years ago, wild fisheries were operating at about 90% and aquaculture items were operating at 10%. Today, you’re having aquaculture tip the scales and doing more than 50% to 60% and wild fisheries dropping to 40% to 45%,” Dresser explained. Rather than competition, one is serving the other.  

Dresser clearly holds a genuine love and affinity for the industry. The seafood industry is an art form as he describes it, not black and white but rather a picture painted by the field’s researchers and stakeholders. That’s why he loves the acronym SIRF, as surfing is a beautiful art form itself; one of balance.  

He truly understands the importance of navigating the wave, not being who makes or forms it, but understanding the wave enough to be able to ride it.  

“So, I love that when we rebranded from the Fishery Scholarship Fund to SIRF, that was perfect, because that’s what we’re doing. We’re surfing,” said Dresser.  

Meet SIRF Board Member Ben Schwartz 

Meet Ben Schwartz, a shellfish aficionado, a road cyclist, a SIRF Board member and Director of Food Safety and Quality Assurance at Harbor Seafood Inc. Schwartz was confirmed to the seat in 2021, based on recommendations from the previous holder, Pete Cardone, and Schwartz’s former Quality Assurance mentor Stephen Thompson. Among the many wonderful attributes of SIRF, Schwartz favors the ability to support research and education through seafood industry funding. Schwartz enjoys being able to honor the legacy of past and present titans of the industry through living and memorial funds.   

Schwartz professes the importance of education; and how vital it is to support the next generation of scientists focused on the seafood industry to benefit consumers. As a part of what he would call a “small-big” industry, Schwartz’s perspective on the seafood industry was shaped early on with his Introduction to SIRF through involvement in the National Fisheries Institute and its Future Leaders Program, which he is grateful for Harbor Seafood ownership sponsoring him for the class of 2016. The program gave him the insight to see the relationships built between the large and small players of the industry. He saw the importance of every piece of the supply chain and their focus on a common goal, providing healthy meals to people all over the world  

Working with SIRF has translated directly into his daily work with Food Safety Quality Assurance (FSQA), as SIRF supports and funds different research projects related to FSQA. Schwartz travelled with Margaret Malkoski, SIRF’s scientific liaison to visit Dr. Dan Distel at the marine science center of Northeastern University, where a DNA database for commercially traded seafood was funded to help combat seafood fraud.   

There are some aspects of the seafood industry that have been eye opening for Schwartz since working with SIRF. Working with the Board gave him a stronger understanding of how the industry can support research and development. The SIRF funds focus more on applied scientific and research fields, and is a side of the industry most are not as well-versed in.   

The Board itself is built of all different backgrounds and works as a whole body with a variety of perspectives and voices. Bringing different views together to create one voice   is of the utmost importance. Guiding such an immense industry, Schwartz takes a lot of inspiration from former SIRF Board Member and founder of Harbor Seafood Pete Cardone, whom he describes as a big proponent of detail-oriented research and charitable endeavors that helped to support the seafood industry. Schwartz’s goal is to make clear lines of communication that allow and encourage collaboration.   

In 2020, the FDA launched an initiative called the “New Era of Smarter Food Safety Blueprint”. It has four main pillars: tech-enabled traceability, smarter tools and approaches for prevention and outbreak response, new business models, and retail modernization. Still working to be fully implemented by the FDA, it can be difficult to apply new regulations for such a vast industry. 

For Schwartz, these pillars are a large part of his daily routine; traceability and foodborne illness prevention are at the forefront of food safety and quality assurance. He underlines the importance of advancing technology for traceability in such a complex category.   

In the same vein of technology and traceability, the future of safety in the seafood industry grows as demand heightens. Seafood has always fallen into the healthy alternative category; however, the stigma surrounding the food hasn’t left. Schwartz explains that seafood is always the scapegoat when it comes to food poisoning, not the appetizer or the drinks; it must have been the fish. The focus on food safety in the future is to provide confidence to consumers.  

Working with other companies, institutions, industries, and academia, like SIRF, will allow the development of new tools to help FSQA and allow for more efficiency as well.    

The 2024 Gorton Cup

This year marked the 30th anniversary of the Annual Gorton Cup Hockey Game. A beloved tradition, the game took place at Boston University’s Walter Brown Arena on Sunday, March 10. 

The game was played in honor of longtime NFI President, the late John Connelly. His wife, Margaret Connelly, ceremoniously dropped the puck to initiate the game. The fundraiser raised $9,280 in pledged donations for the Seafood Industry Research Fund’s John P. Connelly Memorial Fund, which was established in September 2023. 

The game’s final score was 7-3 with Seafood All Stars winning.    

Photo credit to Adrienne Arnold.